EP-1497: Predictive factors of nodal response to neoadjuvant RTCT in pts affected by LARC
نویسندگان
چکیده
منابع مشابه
Predictive factors for response to neoadjuvant therapy in breast cancer.
Within 2 decades, neoadjuvant therapy (NAT) has become a standard treatment option in breast cancer. The advantage of NAT is the ability to monitor the treatment effect. Pathological complete response (pCR) after NAT is a very good predictor for long-term outcome. Clinical factors, such as age and body mass index, as well as recently identified biomarkers can predict the chance of achieving a p...
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Since 2005, major progresses have been made in the neoadjuvant treatment of HER2-positive breast cancer. Trastuzumab introduction associated with chemotherapy has been the first major step leading to the improvement of the complete pathological response rate and, like in the adjuvant studies, better survivals. Dual HER2 blockade has been the next step and trastuzumab is associated now with othe...
متن کاملPredictive Factors of the Response of Rectal Cancer to Neoadjuvant Radiochemotherapy
Locally advanced rectal cancer is currently treated with pre-operative radiochemotherapy (pRCT), but the response is not uniform. Identification of patients with higher likelihood of responding to pRCT is clinically relevant, as patients with resistant tumors could be spared exposure to radiation or DNA-damaging drugs that are associated with adverse side effects. To highlight predictive biomar...
متن کاملPredictive Factors for the Response of Local and Advanced Rectal Cancer to Neoadjuvant Rct
Rectal cancer is an aggressive form of cancer whose treatment follows the next steps: neoadjuvant therapy, surgical excision, and postoperative therapy.Currently, they are trying to identify some predictive factors related to the response to neoadjuvant therapy. Among these factors there are: the characteristics of the tumor according to the TNM classification; the character of the tumor by mon...
متن کاملIs Tc99m-MIBI scintigraphy a predictor of response to pre-operative neoadjuvant chemotherapy in Osteosarcoma?
Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Materials and Methods: Twenty-five patients (12 males and 13 females, aged between 8 and...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)31806-1